After attack on jeep, Israeli army kills 4 in Gaza

GAZA CITY, Gaza Strip (AP) ? Palestinian militants fired an anti-tank missile at an Israeli jeep patrolling the border with Gaza and the Israelis fired back into the Palestinian territory, killing four civilians, officials and witnesses said.

Israel's military said four of its soldiers were wounded in the missile attack, one of them seriously. Ashraf al-Kidra, a Gaza health ministry spokesman, said all four Palestinians killed were civilians between the ages of 16 and 18 and that among the 25 wounded were some children.

The military wing of the leftist Popular Front for the Liberation of Palestine took responsibility but it still remains unclear who in fact was behind the attack. The PFLP often takes credit for attacks that later turn out to be the work of Hamas or Islamic Jihad militants.

Gaza militants often fire rockets from the Israel-Gaza border area toward nearby Israeli communities and low-level clashes with the Israeli military are common. But when casualties are involved, particularly civilians, the potential for escalation grows significantly.

Both sides threatened retaliation, and previous such incidents have unfolded into days of Palestinian rocket attacks and retaliatory Israeli strikes.

Later Saturday, some 25 Palestinian rockets rained on southern Israel, though they caused no injuries or damage, the military said. It said at least one of the projectiles was intercepted by the "Iron Dome" missile defense system. The military informed residents to stay close to home in case of further rocket attacks.

Palestinian officials said that an Israeli airstrike later killed one Islamic Jihad militant and wounded two others as they were attempting to fire rockets toward Israel. The Israeli military confirmed the strike.

Witnesses said that following the large explosion that started the incident, Israel retaliated to the attack on the jeep with tank and machine gun fire toward residential areas at the al-Muntar hill in the central part of the territory, hitting people who were returning from a funeral east of Gaza City.

Rami Harra said his 17-year-old brother Muhammad Harra was killed in the strike.

"He was at home when the explosion took place. He went out to see what happened and when he started to help evacuating wounded people who were on the ground another shell hit the place and killed him," he said outside the morgue. "Why did they kill him? I can't believe my eyes that I am seeing his dead body."

In a first response to Saturday's incident, Israeli Defense Minister Ehud Barak said the military had responded aggressively to the attack and will "consider further reaction in the coming days."

"We will not allow the escalation on the fence to go unanswered," he said.

The Israeli military said it holds Gaza's Hamas rulers responsible for the attack and that it "will not tolerate" such incidents.

In a text message to reporters, Hamas spokesman Fawzi Barhoum threatened to respond.

"Targeting civilians is a dangerous escalation that cannot be tolerated. The resistance has the full right to respond to the Israeli crimes," he said.

Israel carried out a broad military offensive in Gaza nearly four years ago in response to years of near daily rocket fire. Major salvos from Gaza have subsided since then, but sporadic rocket fire has continued.

Gaza's Islamist Hamas rulers have largely refrained from rocket attacks since the devastating Israeli military offensive that killed hundreds of Palestinians.

Hamas, which has killed hundreds of Israelis in suicide bombings and other attacks, remains virulently anti-Israel in its rhetoric but has sought to keep things quiet as it consolidates control of Gaza, which it seized five years ago during a brief civil war against the rival Fatah movement.

Still, it is under pressure from smaller groups to prove that it remains in confrontation with the Jewish state.

The territory is home to numerous militant groups, including murky al-Qaida-inspired organizations that do not answer to Hamas. Gaza has also been flooded with weapons in recent years, many of them believed to have been smuggled from northern Africa and into Gaza through tunnels under the Egyptian border.

Source: http://news.yahoo.com/attack-jeep-israeli-army-kills-4-gaza-175914332.html

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IBM surprised by Avantor lawsuit, calls claims exaggerated

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Travelogue: From San Jose to Portland, Oregon ? Travels With Pain

Hey look, it?s a new Travels With Pain post! Bet you never thought you?d see one of these again.?

This one is much less a how-to post, and much more a ?my mom wants me to write travelogues about my trip with my husband to Oregon to visit his family.? But as I?m still traveling with pain, it?s still on-topic. Sort of.?

Without further ado?

Day 1: San Jose to Ashland via I-5

Yup, we drove to Oregon all right. Took us about six and a half hours. No major traffic snarls, no mountainsides on fire, no highway construction shut down the Interstate. And the gas station-mini-mart-restaurant-horror movie location of Pollard Flat was closed for the season. Which pretty much takes care of anything interesting that might have happened on Day 1.?

Pain tally: Sitting in a car for 6.5 hours is uncomfortable even if you?re a hale and healthy human being (like my husband). I took my medications on time, kept hydrated, insisted on stopping to pee on a regular basis, and thus was in good shape when we arrived in Ashland.?

Night 1 ? Night 2: Ashland

We managed to miss the Oregon Shakespeare Festival by about three hours. And while I wasn?t hurting, I was definitely tired, so we bagged any notion of running around sightseeing and stayed camped in Ashland for the duration.?

Dinner both nights took place at the Standing Stone Brewery, which was much, much better than I expected. I do not like brew pub food. It always ends up tasting vaguely like beer and day-old deep fryer fat to me. Standing Stone is now officially the exception. They?re very big on local sustainable food and drink, if you?re into that sort of thing. (We are.) Their home-brewed beers are exceptional, if you?re into that sort of thing. (I?m not. Husband is. I?m taking his word for it.) Their burgers are yummy. They?ve got plenty of not-beef options, and I suspect that they?d be about medium friendly to serious dietary restrictions.?

We stayed at the Arden Forest Inn. I?ve stayed in literally dozens of inns and hotels since I declared the Arden Forest to be my favorite B&B ever. To be perfectly frank, the Arden Forest doesn?t have the biggest or lushest rooms. (Of course they don?t have the biggest or lushest prices either.) They could use to replace their mattresses and they don?t have jacuzzi tubs.?

That said, I have never ever enjoyed talking to B&B hosts more than I enjoy talking to Bill & Corbett. It?s not at every inn that you can while away the morning talking about the deepest nature of religion and spirituality, the history of gay rights in America, and the possible future of American culture. Among other things.?

Day 3: Ashland to Hillsboro (a suburb of Portland)

Hey look, we?re on I-5 again. Yippee. Actually, I-5 is prettier in Oregon than it is in California. But it still goes by mighty fast, and if you?ve got big-rig fear it?s probably not the route for you.?

We drove. We stopped to pee. We drove some more. We managed to hit high rush hour in Portland, which is much more impressive than it was almost 20 years ago when I last spend any time here. But at length, we arrived at the Comfort Inn Hillsboro where my mother-in-law had booked us a room.?

Tina, the guest services rep at the desk, was absolutely charming. I got to prove, again, some more, why it?s A Good Thing(tm) to be nice to service people. In the course of checking in, I asked Tina if our room had a king sized bed?citing my husband?s height (6-foot, 4-inches) as the reason we like to have king beds. She said we didn?t, we had a queen, and that she didn?t have any kings available. I was gracious about it, and we chattered happily as she checked us in.?

Long story short, because I was nice to Tina, she decided to upgrade us from a standard queen room to a king with a gigantic jacuzzi tub. Without charging for it.

She totally didn?t have to do that. But because we were nice and gracious and didn?t yell at her or otherwise become jerks upon learning that we probably wouldn?t get our every wish?she went out of her way to try to grant our every wish.?

Funny how that works??

?

Coming soon: Hillsboro, Portland, and the Surprise Bonus Beach House

(Also photos once I deal with some technical difficulties)

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Source: http://travelswithpain.com/2012/11/08/travelogue-from-san-jose-to-portland-oregon/

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Brooke Shields 'appalled' by criticism of mother

Ron Galella/WireImage

Brooke Shields and Teri Shields in 1980.

By Bill Higgins, The Hollywood Reporter

Brooke Shields says she's been "appalled" over the years by what has been written about her mother and former manager, Teri Shields, who died this week at 79 in New York following a long illness related to dementia.

Teri Shields had been criticized for allowing Brooke, then age 11, to be cast as a prostitute in 1978's "Pretty Baby," and then a few years later permitting her teenage daughter to star in a series of sexually provocative commercials for Calvin Klein jeans where she says directly to the camera, "You want to know what comes between me and my Calvins? Nothing."

PHOTOS: Hollywood's notable deaths of 2012

Shields tells The Hollywood Reporter that when she thinks back on her mother acting as her manager, what strikes her is ?how she protected me from so much of what is devastating about being in the entertainment industry -- the rejection, the jealousy, the being screwed-over. The bubble she created around me was the biggest blessing she could have given me. The need to attack her is unnecessary."

The actress acknowledged her mother?s struggle with alcoholism and says this was the cause of her 1995 action to drop her as a manager.

?I had to leave her because of her addiction. If I had a manager now, they wouldn?t last five minutes if they were an alcoholic,? Shields says. ?It was long overdue. I needed to grab the reins and make my own mistakes.?

PHOTOS: 11 of Hollywood's models turned movie stars

Teri, born Theresa Anna Lillian Schmon on Aug. 11, 1933, in Newark, N.J., worked as a hairstylist, a makeup artist for Lord & Taylor and a model before marrying Brooke?s father,?Francis Alexander Shields, in 1964. Brooke was born the following year; Teri and her husband divorced a few months after her birth.

Related content:

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Source: http://todayentertainment.today.com/_news/2012/11/09/15046799-brooke-shields-appalled-by-criticism-of-her-late-mother-teri?lite

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Villagers mourn family among the 52 dead in Guatemalan quake ...

Michael Weissenstein,Sonia Perez D., The Associated Press | Last Updated:Thu, 08 Nov 2012 22:18:49 GMT

Residents walk among rubble after a magnitude 7.4 earthquake struck in San Marcos, Guatemala, Wednesday Nov. 7, 2012. The mountain village, some 80 miles (130 kilometers) from the epicenter, suffered much of the damage with some 30 homes collapsing in its center. There are three confirmed dead and many missing after the strongest earthquake to hit Guatemala since a deadly 1976 quake that killed 23,000. (AP Photo/Moises Castillo)

SAN CRISTOBAL CUCHO, Guatemala - The 10 members of the Vasquez family were found together under the rubble of the rock quarry that had been their livelihood, some in a desperate final embrace, others clinging to the faintest of dying pulses.

As Guatemalans sought Thursday to pick up the pieces after a 7.4-magnitude quake, one family's tragic story came to symbolize the horror of a disaster that killed at least 52 people, and left thousands of others huddling in the cold shadows of cracked adobe buildings, most without electricity or water.

On Thursday, neighbours came to pay their respects. They filed past 10 wooden caskets in the Vasquez family living room, and contemplated the unspeakable future that awaits the family's only surviving son. Justo Vasquez, his wife Ofelia Gomez, six children and two nephews died in the rubble.

Only the oldest son, Ivan, 19, survived. He had stayed in the house when the rest of his family went to the quarry, taking care of some last-minute details to receive his accounting degree ? the first in his family to have a professional career. His father had been saving for a party to celebrate his Nov. 23 graduation.

"He died working," said Antonia Lopez, a sister-in-law of Justo Vasquez. "He was fighting for his kids."

Hundreds of villagers in the humble town of San Cristobal Cucho ran to dig the family out on Wednesday after Guatemala's biggest quake in 36 years. When they uncovered some of the children, one body still warm, two with pulses, they were in the arms of their father, who had tried to shield them from a falling mountain.

The death toll was expected to rise as 22 people remained missing, President Otto Perez Molina told a news conference. Eight were killed in the neighbouring state of Quetzaltenango.

Perez said powerful 7.4-magnitude quake, felt as far as Mexico City 600 miles away, affected as many as 1.2 million Guatemalans. A little more than 700 people were in shelters, with most opting to stay with family or friends, he added.

"They have no drinking water, no electricity, no communication and are in danger of experiencing more aftershocks," Perez said. The president said there had been 70 aftershocks in the first 24 hours after the quake, some as strong as magnitude 5.1.

Damaged homes are among the biggest problems the country will face in the coming days, Perez added.

The Vasquezes were the only ones to die in San Cristobal Cucho, a mountain village of cobblestone streets, where buildings suffered some cracks and damage and early reports said the family had perished in a collapsed house.

Like the rest of several thousand people in town, the Vasquez family was humble, the parents without much education. Most of the people in the town are subsistence farmers or sell things on the streets and in the markets.

"We have never seen a tragedy like this. The whole town is sad," said brother Romulo Vasquez, whose 12-year old son, Ulises, also died at the quarry.

Justo Vasquez and his wife left for work at 5 a.m. Wednesday to the land they rented to quarry white rock that is pulverized to make cinder blocks. They returned later in the morning to eat breakfast, then took six of their seven children and two nephews back to the quarry with them, because the children were on vacation from school.

The oldest child to die was 14-year-old Daisy Vasquez, the youngest 3-year-old Dibel Vasquez.

The oldest son, Ivan, was too distraught to speak or even stay at the red-and-yellow block house where hundreds of people gathered passed by the caskets or waited outside the door marked by candles and just a few flowers. Wood smoke bathed the memorial as more than a dozen women in the back of the house cooked rice, beans, corn and eggs to feed the crowd.

"He was a very good father, he was a very good neighbour," said Antonia Lopez, who was among the many paying respects.

Guatemalans fearing aftershocks huddled in the streets of the nearby city San Marcos, the most affected area, where at least 40 people died. Others crowded inside its hospital, the only building in town left with electricity.

More than 90 rescue workers continued to dig with backhoes at a half-ton mound of sand at a second quarry that buried seven people.

"We started rescue work very early," said Julio Cesar Fuentes of the municipal fire department. "The objective is our hope to find people who were buried."

But they uncovered only more dead. One man was called to the quarry to identify his dead father. When he climbed into the sand pit and recognized the clothing, the son collapsed onto the shoulders of firefighters, crying: "Papa, Papa, Papa."

He and his father were not identified to the news media because other relatives had not been notified of the death.

Volunteers carrying boxes of medical supplies began arriving in the area in western Guatemala late Wednesday.

The quake, which was 20 miles deep, was centred 15 miles off the coastal town of Champerico and 100 miles southwest of Guatemala City. It was the strongest earthquake to hit Guatemala since a 1976 temblor that killed 23,000.

Perez said more than 2,000 soldiers were deployed to help with the disaster. A plane had made at least two trips to carry relief teams to the area.

___

Associated Press writer Ruiz-Goiriena in Guatemala City contributed to this report.

Source: http://www.tonightnewspaper.com/2012/11/08/villagers-mourn-family-guatemala-quake-toll-at-52/

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Stem cell scientists discover potential way to expand cells for use with patients

ScienceDaily (Nov. 8, 2012) ? Canadian and Italian stem cell researchers have discovered a new "master control gene" for human blood stem cells and found that manipulating its levels could potentially create a way to expand these cells for clinical use.

The findings, published November 8 online ahead of print in Cell Stem Cell, usher in a new paradigm for the regulation of human blood stem cells, says co-principal investigator Dr. John Dick, who holds a Canada Research Chair in Stem Cell Biology and is a Senior Scientist at University Health Network's McEwen Centre for Regenerative Medicine and Ontario Cancer Institute (OCI), the research arm of the Princess Margaret Cancer Centre. He is also a Professor in the Department of Molecular Genetics, University of Toronto.

"For the first time in human blood stem cells, we have established that a new class of non-coding RNA called miRNA represents a new tactic for manipulating these cells, which opens the door to expanding them for therapeutic uses," says Dr. Dick.

In 2011, Dr. Dick isolated a human blood stem cell in its purest form -- as a single stem cell capable of regenerating the entire blood system -- paving the way for clinical uses. He also pioneered the cancer stem cell field by identifying leukemia stem cells in 1994 and colon cancer stem cells in 2007.

OCI lead author Dr. Eric Lechman says the research team removed a master control gene -- microRNA 126 (miR-126) -- that normally governs the expression of hundreds of other genes by keeping them silenced, which in turn keeps the stem cells in a non-dividing dormant state. The method was to introduce excess numbers of miR-126 binding sites into the stem cells by using a specially designed viral vector.

"The virus acted like a sponge and mopped up the specific miRNA in the cells. This enabled the expression of normally repressed genes to become prominent, after which we observed a long-term expansion of the blood stem cells without exhaustion or malignant transformation," says Dr. Lechman.

Adds Dr. Dick: "We've shown that if you remove the miRNA you can expand the stem cells while keeping their identity intact. That's the key to long-term stem cell expansion for use with patients." The co-principal investigator was Dr. Luigi Naldini, Director, of the San Raffaele Telethon Institute for Gene Therapy, Milan.

Dr. Dick's research was funded by the Canadian Institutes of Health Research, the Canadian Cancer Society, the Terry Fox Foundation, Genome Canada through the Ontario Genomics Institute, the Ontario Institute for Cancer Research, the Canada Research Chair Program, the Ontario Ministry of Health and Long-Term Care, the Canada Foundation of Innovation, as well as The Princess Margaret Cancer Foundation.

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Story Source:

The above story is reprinted from materials provided by Princess Margaret Hospital, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Eric?R. Lechman, Bernhard Gentner, Peter van?Galen, Alice Giustacchini, Massimo Saini, Francesco?E. Boccalatte, Hidefumi Hiramatsu, Umberto Restuccia, Angela Bachi, Veronique Voisin, Gary?D. Bader, John?E. Dick, Luigi Naldini. Attenuation of miR-126 Activity Expands HSC In?Vivo without Exhaustion. Cell Stem Cell, 2012; DOI: 10.1016/j.stem.2012.09.001

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/EkhcBU95gPw/121108141024.htm

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Senate Democrats won't "mess with Social Security": Reid

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Source: http://news.yahoo.com/senate-democrats-wont-mess-social-security-reid-174641106.html

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International business, government and civil society leaders join ...

International leaders from business, government and NGOs gathered in Singapore today to mark the launch of the new headquarters of TEEB (The Economics of Ecosystems and Biodiversity) for Business Coalition which aims to achieve a shift in corporate behaviour to preserve and enhance, rather than deplete the earth?s natural capital....

Link to original article / Continue Reading...

Constantine Alexander's Blog was launched to share with you international wildlife news, exciting environmental research activities, political action or inaction, and what each of us can do to ensure that the wisdom of nature endures for the benefit of us all as we are mere caretakers of nature for future generations of all species which have a right to thrive in and contribute to a healthy and beautiful world.

Source: http://sierraactivist.org/2012/11/06/international-business-government-and-civil-society-leaders-join-forces-in-global-forum-for-valuing-natural-capital/?utm_source=rss&utm_medium=rss&utm_campaign=international-business-government-and-civil-society-leaders-join-forces-in-global-forum-for-valuing-natural-capital

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